Table 1.
Entrez Symbol | Gene Name | Comparison | RT-PCR Log2 Fold Change | Microarray
|
||
---|---|---|---|---|---|---|
Log2 Fold Change | p-value | FDR | ||||
NOS3 | nitric oxide synthase 3 (endothelial cell) | RvC | 1.17 ± 0.49 *† | 0.47 ± 0.13 | 2.03 e-5 | 0.011 |
NvC | 0.30± 0.44 | 0.29 ± 0.13 | 1.09 e-3 | 0.207 | ||
ICAM1 | intercellular adhesion molecule 1 | RvC | 0.92 ± 0.25 *† | 0.15 ± 0.12 | 0.031 | 0.331 |
NvC | 0.49 ± 0.44 | 0.10 ± 0.12 | 0.114 | 0.640 | ||
VCAM1 | vascular cell adhesion molecule 1 | RvC | 0.23 ± 0.78 | −0.22 ± 0.29 | 0.161 | 0.641 |
NvC | −0.67 ± 0.43 * | −0.66 ± 0.29 | 9.86 e-4 | 0.203 | ||
KLF2 | Kruppel-like factor 2 (lung) | RvC | 0.84 ± 0.31 *† | 0.33 ± 0.11 | 1.30 e-4 | 0.025 |
NvC | 0.43 ± 0.25 * | 0.26 ± 0.11 | 7.47 e-4 | 0.176 | ||
KLF4 | Kruppel-like factor 4 (gut) | RvC | 0.95 ± 0.35 * | 0.47 ± 0.13 | 1.86 e-5 | 0.010 |
NvC | 0.53 ± 0.33 * | 0.26 ± 0.13 | 2.06 e-3 | 0.261 | ||
SELE | selectin E | RvC | −0.86 ± 0.63 * | −0.86 ± 0.32 | 2.57 e-4 | 0.032 |
NvC | −0.94 ± 0.51 * | −0.77 ± 0.32 | 6.35 e-4 | 0.157 | ||
CCL2 | chemokine (C-C motif) ligand 2 | RvC | −0.69 ± 0.37 * | −0.19 ± 0.11 | 5.53 e-3 | 0.153 |
NvC | −0.38 ± 0.32 * | −0.08 ± 0.11 | 0.168 | 0.706 |
Data represents RT-PCR (n=8/group) and microarray analysis (n=4/group). RvC, reversal versus control. NvC non-reversal versus control.
indicates p<0.05 significance versus control RT-PCR,
indicates significance p<0.05 of reversal v non-reversal by RT-PCR expression levels. Uncertainty in PCR is mean +/− standard deviation for microarray mean +/− 95% confidence