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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Sep 3;35(11):2354–2365. doi: 10.1161/ATVBAHA.115.305775

Table 1.

Comparison of microarray genes to RT-PCR analyses for selected genes known to mediate arteriogenesis

Entrez Symbol Gene Name Comparison RT-PCR Log2 Fold Change Microarray
Log2 Fold Change p-value FDR
NOS3 nitric oxide synthase 3 (endothelial cell) RvC 1.17 ± 0.49 * 0.47 ± 0.13 2.03 e-5 0.011
NvC 0.30± 0.44 0.29 ± 0.13 1.09 e-3 0.207
ICAM1 intercellular adhesion molecule 1 RvC 0.92 ± 0.25 * 0.15 ± 0.12 0.031 0.331
NvC 0.49 ± 0.44 0.10 ± 0.12 0.114 0.640
VCAM1 vascular cell adhesion molecule 1 RvC 0.23 ± 0.78 −0.22 ± 0.29 0.161 0.641
NvC −0.67 ± 0.43 * −0.66 ± 0.29 9.86 e-4 0.203
KLF2 Kruppel-like factor 2 (lung) RvC 0.84 ± 0.31 * 0.33 ± 0.11 1.30 e-4 0.025
NvC 0.43 ± 0.25 * 0.26 ± 0.11 7.47 e-4 0.176
KLF4 Kruppel-like factor 4 (gut) RvC 0.95 ± 0.35 * 0.47 ± 0.13 1.86 e-5 0.010
NvC 0.53 ± 0.33 * 0.26 ± 0.13 2.06 e-3 0.261
SELE selectin E RvC −0.86 ± 0.63 * −0.86 ± 0.32 2.57 e-4 0.032
NvC −0.94 ± 0.51 * −0.77 ± 0.32 6.35 e-4 0.157
CCL2 chemokine (C-C motif) ligand 2 RvC −0.69 ± 0.37 * −0.19 ± 0.11 5.53 e-3 0.153
NvC −0.38 ± 0.32 * −0.08 ± 0.11 0.168 0.706

Data represents RT-PCR (n=8/group) and microarray analysis (n=4/group). RvC, reversal versus control. NvC non-reversal versus control.

*

indicates p<0.05 significance versus control RT-PCR,

indicates significance p<0.05 of reversal v non-reversal by RT-PCR expression levels. Uncertainty in PCR is mean +/− standard deviation for microarray mean +/− 95% confidence