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. 2015 Oct 22;9:71. doi: 10.1186/s12918-015-0220-9

Table 4.

Summary of predicted disease effects on liver regeneration

Disease Model Mass Recovery Priming Replication IL-6 Signaling GF ECM
(1) Non-alcoholic Steatohepatitis Suppressed Low Low Low High High
(2) Alcoholic Steatohepatitis Suppressed Sustained Low Sustained Low High
(3) Toxin-induced Cirrhosis Suppressed High Low High Low High
(4) Allotaxin-induced Diabetes Delayed High Delayed & low Sustained Low Low