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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Stem Cells. 2015 Feb;33(2):468–478. doi: 10.1002/stem.1851

Figure 6. Effect of hASC against myelotoxicity of CS was reproduced by hASC conditioned medium as well as by TSG-6.

Figure 6

C57BL/6 mice were exposed to ambient air or 3-day CS and injected i.v. with following treatment groups: 1) PBS; 2) 3 × 105 hASC; 3) conditioned media from non-transfected hASC(ASCNT), 4) & 5) from hASC transfected with TSG-6 siRNA (ASCTS) with or without supplement of 0.2 μg rhTSG-6, or 6) from hASC transfected with scrambled siRNA (ASCSC); 7) 2 μg rhTSG-6. Cycling progenitors (right) demonstrates a more sensitive response to treatment than absolute number of progenitors (left). Mean ± SEM, n = 6/group; ap < 0.05 (vs. AC); bp < 0.05, (vs. vehicle).