Table 5. Frequentist and Bayesian meta-analyses of within group and between group differences of dietary interventions on predicted ASCVD risk for each subgroup.
Predicted Risk, % (Frequentist) | White, lower-risk | White, higher-risk | African-American, lower-risk | African-American, higher-risk | |
Low CHO (within group) | Baseline | 1.19 (0.90, 1.48) | 4.88 (4.01, 5.74) | 1.81 (1.35, 2.26) | 6.38 (4.98, 7.78) |
Outcome | 0.99 (0.72, 1.26) | 4.03 (3.17, 4.88) | 1.50 (1.04, 1.97) | 5.08 (3.63, 6.53) | |
Mean (95% CI) | -0.20 (-0.27, -0.13) | -0.85 (-1.10, -0.60) | -0.30 (-0.41, -0.19) | -1.30 (-1.72, -0.88) | |
p | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | |
Low FAT (within group) | Baseline | 1.22 (0.84, 1.60) | 4.90 (3.89, 5.92) | 1.85 (1.24, 2.46) | 6.48 (4.71, 8.25) |
Outcome | 1.13 (0.75, 1.51) | 4.49 (3.44, 5.54) | 1.74 (1.11, 2.37) | 5.94 (4.13, 7.74) | |
Mean (95% CI) | -0.10 (-0.17, -0.02) | -0.41 (-0.72, -0.10) | -0.11 (-0.24, 0.02) | -0.54 (-1.04, 0.04) | |
p | 0.01 | 0.01 | 0.086 | 0.036 | |
Between Group Differences | Mean (95% CI) | -0.10 (-0.20, -0.01) | -0.44 (-0.83, -0.06) | -0.19 (-0.35, -0.03) | -0.76 (-1.38, -0.14) |
p | 0.03 | 0.025 | 0.02 | 0.02 | |
Predicted Risk, % (Bayesian) | |||||
Low CHO (within group) | Baseline | 1.18 (0.89, 1.48) | 4.89 (3.98, 5.81) | 1.80 (1.33, 2.29) | 6.38 (4.88, 7.84) |
Outcome | 0.98 (0.70, 1.27) | 4.01 (3.11, 4.91) | 1.49 (1.00, 1.98) | 5.03 (3.50,6.55) | |
Mean (95% CrI) | -0.20 (-0.61, 0.21) | -0.88 (-2.15, 0.40) | -0.31 (-1.01, 0.37) | -1.35 (-3.48, 0.75) | |
Probability Reduced Risk | 84.1% | 91.6% | 82.1% | 89.9% | |
Low FAT (within group) | Baseline | 1.15 (0.79, 1.52) | 4.83 (3.80,5.88) | 1.80 (1.18, 2.42) | 6.37 (4.58, 8.24) |
Outcome | 1.05 (0.68, 1.42) | 4.39 (3.34, 5.49) | 1.67 (1.05, 2.30) | 5.78 (3.99,7.66) | |
Mean (95% CrI | -0.10 (-0.61, 0.40) | -0.44 (-1.94, 1.00) | -0.13 (-1.00, 0.73) | -0.59 (-3.19, 1.94) | |
Probability Reduced Risk | 66.7% | 72.5% | 62.1% | 68.2% | |
Between Group Differences | Mean (95% CrI) | -0.11 (-0.21, 0.01) | -0.44 (-0.84, 0.02) | -0.19 (-0.37, -0.12) | -0.76 (-1.44, -0.06) |
Probability LoCHO Superior | 98.1% | 98.1% | 98.1% | 98.3% |