Table 3.
Mean seasonal RSV-attributable burden of GP episodes, hospital admissions and deaths due to respiratory disease among adults by age group; United Kingdom 1995-2009
| GP episodes | Hospitalisations | Deaths | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) | Episodes/100,000 population (range) | N | % of events attributable to RSV** | RSV:influenza ratio† |
Hospitalisations/100,000 population (range) | N | % of events attributable to RSV** | RSV:influenza ratio† | Deaths/100,000 population (range) | N | % of events attributable to RSV** | RSV:influenza ratio† |
| Respiratory disease | ||||||||||||
| 18-49 | 677 (443–850) | 176534 | 3.3 | 0.6:1 | 4 (3–5) | 1033 | 1.4 | 0.3:1 | 1 (0–1) | 144 | 4.2 | 0.8:1 |
| 50-64 | 1325 (928–1542) | 136469 | 6.1 | 1.1:1 | 30 (22–36) | 3067 | 5.2 | 0.8:1 | 6 (5–7) | 656 | 5.9 | 0.9:1 |
| 65-74 | 1742 (1259–2038) | 86201 | 6.6 | 1.6:1 | 86 (62–101) | 4236 | 5.8 | 0.8:1 | 29 (21–33) | 1416 | 5.7 | 0.9:1 |
| 75+ | 2175 (1554–2516) | 88043 | 7.5 | 1.6:1 | 234 (180–291) | 9463 | 6.8 | 0.9:1 | 155 (108–213) | 6266 | 5.9 | 0.7:1 |
| Acute upper respiratory disease | ||||||||||||
| 18-49 | 394 (261–489) | 102728 | 3.9 | 0.8:1 | - | - | - | - | - | - | - | - |
| 50-64 | 590 (430–696) | 60757 | 7.8 | 1.7:1 | - | - | - | - | - | - | - | - |
| 65-74 | 557 (433–701) | 27580 | 8.4 | 2.5:1 | - | - | - | - | - | - | - | - |
| 75+ | 528 (407–659) | 21372 | 10.1 | 2.4:1 | - | - | - | - | - | - | - | - |
| Pneumonia and Influenza | ||||||||||||
| 18-49 | 51 (17–97) | 13217 | 5.8 | 0.1:1 | 2 (2–3) | 615 | 5.8 | 0.6:1 | 0 (0–1) | 103 | 5.9 | 0.8:1 |
| 50-64 | 88 (40–145) | 9031 | 10.4 | 0.2:1 | 7 (5–9) | 736 | 7.2 | 1.0:1 | 4 (3–5) | 391 | 7.3 | 0.9:1 |
| 65-74 | 116 (66–167) | 5755 | 13.6 | 0.4:1 | 20 (15–26) | 987 | 7.3 | 1.0:1 | 17 (12–20) | 821 | 6.7 | 0.8:1 |
| 75+ | 196 (112–279) | 7944 | 11.2 | 0.6:1 | 80 (51–109) | 3238 | 7.7 | 1.0:1 | 121 (86–164) | 4884 | 7.1 | 0.7:1 |
| Bronchitis/ Bronchiolitis | ||||||||||||
| 18-49 | 229 (163–264) | 59799 | 6.0 | 0.7:1 | 2 (1–2) | 444 | 4.3 | 0.5:1 | 0 (0–0) | 4 | 6.2 | 0.6:1 |
| 50-64 | 653 (458–759) | 67269 | 9.7 | 1.2:1 | 7 (5–9) | 764 | 8.3 | 0.7:1 | 0 (0–1) | 43 | 17.2 | 1.0:1 |
| 65-74 | 1088 (776–1257) | 53839 | 11.0 | 1.8:1 | 19 (14–22) | 952 | 9.1 | 0.7:1 | 1 (1–2) | 66 | 12.6 | 1.0:1 |
| 75+ | 1594 (1147–1858) | 64540 | 12.3 | 1.8:1 | 75 (56–91) | 3037 | 10.6 | 0.8:1 | 5 (3–7) | 204 | 10.2 | 0.8:1 |
| COPD | ||||||||||||
| 18-49 | 23 (14–31) | 6034 | 1.2 | 1.7:1 | 0 (0–0) | 0 | 0.0 | 0:1 | 0 (0–0) | 15 | 3.8 | 0.7:1 |
| 50-64 | 77 (49–100) | 7943 | 2.7 | 2.2:1 | 14 (10–17) | 1484 | 5.8 | 0.8:1 | 3 (2–4) | 296 | 8.9 | 1.1:1 |
| 65-74 | 136 (72–206) | 6734 | 2.7 | 2.9:1 | 45 (32–52) | 2229 | 6.5 | 0.9:1 | 14 (9–17) | 685 | 7.5 | 0.9:1 |
| 75+ | 82 (44–121) | 3300 | 1.7 | 1.4:1 | 75 (55–88) | 3052 | 7.4 | 1.2:1 | 36 (27–48) | 1456 | 6.5 | 0.8:1 |
| Cardiorespiratory | ||||||||||||
| 18-49 | - | - | - | 1 (1–3) | 376 | 0.4 | 0.1:1 | 1 (1–1) | 213 | 2.8 | 1:1 | |
| 50-64 | - | - | - | 18 (12–22) | 1837 | 1.3 | 0.5:1 | 8 (6–10) | 859 | 3.4 | 0.9:1 | |
| 65-74 | - | - | - | 56 (39–67) | 2780 | 1.6 | 0.6:1 | 37 (25–44) | 1826 | 3.5 | 0.9:1 | |
| 75+ | - | - | - | 174 (126–204) | 7042 | 2.3 | 0.7:1 | 198 (155–259) | 8028 | 4.1 | 0.8:1 | |
| Antibiotic prescriptions | ||||||||||||
| 18-49 | 610 (442–715) | 159223 | 2.6 | 0.7:1 | - | - | - | - | - | - | - | - |
| 50-64 | 1449 (1081–1750) | 149229 | 5.3 | 1.4:1 | - | - | - | - | - | - | - | - |
| 65-74 | 1999 (1556–2520) | 98921 | 6.0 | 2:1 | - | - | - | - | - | - | - | - |
| 75+ | 2261 (1809–2938) | 91535 | 6.3 | 2.1:1 | - | - | - | - | - | - | - | - |
N = Seasonal number of specified RSV-attributable events in the UK
Proportion = per 100,000 population
Range = range of estimates per season
GP = general practice, COPD = chronic obstructive pulmonary disease
*Outcomes refer to the ‘Primary’ cause for hospitalisation for HES, or as the ‘Any mention’ cause of death for ONS. For the GPRD data there is no ordered listing or ranking of diagnostic codes
**% of RSV-attributable events among all events due to outcome
† ratio of proportions/100,000 RSV/[influenza A + B]