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. 2015 Oct 21;10(10):e0139262. doi: 10.1371/journal.pone.0139262

Table 2. Summary of Association with the Risk of PAD.

dbSNP ID Chr. Gene Phase Number of samples MAF OR 95%CI P
Cases Controls Cases Controls
rs9584669 13 IPO5/RAP2A GWAS 785 3383 0.04 0.06 0.60 0.45–0.79 2.76 x 10−4
Replication 2379 16751 0.03 0.05 0.57 0.48–0.66 2.10 x 10−11
Combined* 3164 20134 0.03 0.05 0.58 0.50–0.66 6.78 x 10−14
rs6842241 4 EDNRA GWAS 785 3372 0.36 0.30 0.76 0.68–0.85 2.36 x 10−6
Replication 2342 16750 0.33 0.30 0.88 0.83–0.93 9.09 x 10−5
Combined* 3127 20122 0.34 0.30 0.85 0.80–0.90 5.32 x 10−9
rs2074633 7 HDAC9 GWAS 785 3382 0.43 0.38 1.24 1.11–1.38 1.41 x 10−4
Replication 2363 16751 0.41 0.38 1.13 1.06–1.20 7.63 x 10−5
Combined* 3148 20133 0.41 0.38 1.16 1.10–1.22 8.43x 10−8

ID; identifier, Chr.; chromosome, MAF; minor allele frequency, OR; odds ratio, CI; confidence interval.

*; P value was calculated by Mantel-Haenszel test.