Skip to main content
. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Dev Dyn. 2015 Sep 2;244(11):1439–1455. doi: 10.1002/dvdy.24322

Figure 11.

Figure 11

No evidence for hypoxia in cloche mutant retinas. A-C. In situ hybridization for phd3 mRNA in wild-type normoxic embryos (A), wild-type hypoxic embryos showing positive hybridization signals (B), and clo−/− embryos showing no hybridization signal (C). D. Quantitative RT-PCR of whole embryo tissues shows significant upregulation of phd3 expression (*p<0.001) in hypoxic (hyp) as compared to normoxic (norm) embryos, but not in clo−/− as compared to wild-type embryos (n.s., not significant; p=0.53). Scale bar in A (applies to all images) = 50 μm.