Figure 2.
Histology of wild-type (A,C,E) and clo−/− (B,D,F) eyes at 30 hpf, 48 hpf, and 72 hpf. RPE, retinal pigmented epithelium; RN, retinal neuroepithelium; LE, lens; VE, vascular endothelial cells; IPL, inner plexiform layer; ONH, optic nerve head; GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer; OPL, outer plexiform layer. In F, asterisk (*) denotes gap between lens epithelium and developing lens fibers; wide arrow points to pyknotic cells in INL. Scale bar (in A, applies to all) = 50 μm.