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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Virology. 2015 Aug 29;485:313–321. doi: 10.1016/j.virol.2015.08.006

Fig. 2.

Fig. 2

Dose–response of NRTIs in activated CD4+ T cells challenged with molecular clones that code, or do not code, for Vpx. Percent inhibition (y-axis) of CD4+ T cells treated with increasing concentrations (x-axis) of AZT (A), 3TC (B), TDF (C), RAL (D) and ETR (E) before challenge with SIV (filled squares), SIVΔVpx (open squares), RT-SHIV (filled circles) and RT-SHIVΔVpx (open circles). Dashed line transects curve to show where 50% inhibition occurs. Significant differences in dose–response curves are indicated with an asterisk (*). Data points depict the means and standard error of the means from three to four independent experiments.