Figure 5.

Mandible development in wild type, Fgfr1^ccko and Fgfr1/2^dcko mice. (A) E14.5, (B) E15, and (D) P0 wild type mouse heads stained with alizarin red & alcian blue. (A′) E14.5, (B′) E15 and (D′) P0 Fgfr1/2^dcko heads stained with alizarin red & alcian blue. (C) E15 and (E) P0 Fgfr1^ccko heads stained with alizarin red & alcian blue. Arrows indicate the developing mandible with Mechel’s cartilages stained blue and ossified bones stained red. Noted the same magnification of specimens shown in A–E. At least three specimens of each genotype were examined at each stage.