Table 2.

Factors associated with disease-specific death

Factor	Univariate P	Multivariate P	Multivariate HR (95% CI)
Age (>60 vs ≤60 years)	0.51	–	–
Sex (male vs female)	0.22	–	–
Location (pelvis vs other)	0.75	–	–
Size
10–20 cm vs <10 cm	0.51	0.44	1.2 (0.8–1.8)
≥20 cm vs <10 cm	0.59	0.07	1.5 (1.0–2.3)
Radiation-associated (yes vs no)	0.14	0.37	1.5 (0.6–3.7)
Histology*
Dedifferentiated, round cell & pleomorphic LPS, sarcoma NOS	<0.001	<0.001	3.4 (2.3–5.1)
Low-grade leiomyosarcoma	0.98	0.78	1.2 (0.3–4.9)
High-grade leiomyosarcoma	<0.001	<0.001	3.9 (2.5–6.3)
Solitary fibrous tumor	0.04	0.02	2.2 (1.1–4.5)
Malignant peripheral nerve sheath tumor	<0.001	<0.001	4.3 (2.0–9.2)
Translocation-associated sarcoma	<0.001	<0.001	3.8 (2.0–7.3)
Number of organs resected (≥3 vs <3)	<0.001	0.002	1.9 (1.3–2.8)
Vascular resection (yes vs no)	0.88	–	–
Completeness of resection (R2 vs R0/R1)	<0.001	<0.001	2.5 (1.6–3.8)

^*compared to well-differentiated and myxoid liposarcoma

CI, confidence interval; LPS, liposarcoma; NOS, not otherwise specified