Table 3.

Factors associated with local recurrence

Factor	Univariate P	Multivariate P	Multivariate HR (95% CI)
Age (>60 vs ≤60 years)	0.07	0.002	0.63 (0.5–0.8)
Sex (male vs female)	0.47	–	–
Location (pelvis vs other)	0.002	0.34	0.8 (0.5–1.3)
Size
10–20 cm vs <10 cm	0.01	0.08	1.6 (0.9–2.8)
≥20 cm vs <10 cm	<0.001	0.01	2.1 (1.2–3.8)
Radiation-associated (yes vs no)	0.77	–	–
Histology*
Dedifferentiated, round cell & pleomorphic LPS, sarcoma NOS	<0.001	<0.001	2.3 (1.7–3.1)
Low-grade leiomyosarcoma	0.1	0.31	0.5 (0.1–2.0)
High-grade leiomyosarcoma	0.003	0.55	0.8 (0.5–1.5)
Solitary fibrous tumor	0.008	0.03	0.1 (0.02–0.8)
Malignant peripheral nerve sheath tumor	0.81	0.92	1.0 (0.4–2.6)
Translocation-associated sarcoma	0.32	0.91	1.1 (0.4–2.9)
Number of organs resected (≥3 vs <3)	0.003	0.86	1.0 (0.7–1.6)
Vascular resection (yes vs no)	0.03	0.54	0.8 (0.5–1.5)
Completeness of resection (R1 vs R0)	<0.001	<0.01	1.5 (1.1–1.9)

^*compared to well-differentiated and myxoid liposarcoma

CI, confidence interval; LPS, liposarcoma; NOS, not otherwise specified