Fig 2. Serum sCD40L improves the killing of L. infantum by infected macrophages.

L. infantum infection levels in macrophages were assessed after 72 h incubation with 20% serum from subjects infected with L. infantum in the presence of isotype control antibody (10 μg/ml) or anti-human CD40L (10 μg/ml). The (A) number of infected macrophages/100 macrophages and; (B) number of amastigotes/100 macrophages are shown. n = 14, *Paired t test and ** Wilcoxon signed rank test.