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. 2015 Oct 21;10(10):e0141345. doi: 10.1371/journal.pone.0141345

Fig 4. Mechanical loading altered diameters of collagen fibrils in area-dependent manner.

Fig 4

Nonmineralized-bone collagen fibrils were randomly photographed at 46000-fold magnification using transmission electron microscopy (TEM), and diameters of collagen fibrils were measured in 4 groups (n≥3 samples, n≥500 collagen fibrils per group) Measurement of fibril diameters in cortical areas showed the same impact of exercise on the diameters in both groups.