Table 1.
Overview of potential virulence characteristics of Streptococcus uberis and their in vitro manifestation in FSL Z1-048 and FSL Z1-124, which were virulent and non-virulent, respectively, in experimental challenge studies [36]
| Virulence trait | FSL Z1-048 | FSL Z1-124 |
|---|---|---|
| Growth in milka | ↓b | ↑ |
| Resistance to macrophage killing | ↑ | ↓ |
| Resistance to PMN killing | ↓ | ↑ |
| Adhesion | ↑ | ↓ |
| Invasion | ↓ | ↑ |
| Biofilm formation | ↓ | ↑ |
| Sua | ↓ | ↑ |
aBased on Tassi et al. [36]
b↑ Means that the trait as observed in vitro would be expected to increase virulence in vivo compared to the other strain and ↓ means that the trait as observed in vitro would be expected to decrease virulence in vivo.