Table 3. Risk of MACE for patients with different cumulative prescription days of ARB.
Variables | N | Event, n | Adjusted HR (95% CI) a , b , c | P-value |
---|---|---|---|---|
Duration | <0.001 | |||
non-users | 1061 | 497 | 1 | |
1–90 days | 224 | 121 | 1.00(0.81–1.23) | |
91–365 days | 237 | 128 | 0.87(0.71–1.08) | |
366–730 days | 136 | 64 | 0.72(0.55–0.95)* | |
731–1095 days | 78 | 30 | 0.51(0.35–0.75)*** | |
1096–1460 days | 42 | 10 | 0.34(0.18–0.64)* | |
1460–1825 days | 22 | 1 | 0.06(0.01–0.45)* |
a HR = hazard ratio; CI = confidence interval.
b Adjusted for gender, age group, and comorbidities.
c *P < 0.05; ***P < 0.001.