Fig 1. G _ES at arginines and/or lysines does not identify the GBS on a protein.

G _ES for Arg/Lys residues are mapped using 2DSE plots for multiple GAG-binding proteins including (a) antithrombin, (b) thrombin, (c) FGF2, (d) HS3ST3A1, (e) HS3ST1 and (f) HS2ST1. The maps reveal that GAG-binding site Arg/Lys residues may not always possess high G _ES and not all Arg/Lys with high G _ES on a protein are part of the GAG-binding site.