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*EDSS: Expanded disability status scale [22].
| Patients | Non-MS full Siblings | Healthy Controls | p-value | |
|---|---|---|---|---|
| N (female/male) | 39 (35/4) | 31 (20/11) | 30 (25/5) | 0.03 |
| Age (years) | [32–69] 49.7±10.1 | [30–67] 50.6±11.0 | [30–67] 50.6±11.3 | 0.88 |
| Age at disease onset (years) | [17–56] 32.4±8.0 | NA | NA | NA |
| Disease Duration (DD, years) | [3–41] 17.2±9.3 | NA | NA | NA |
| EDSS* | [0–6.5] median 2.5 | NA | NA | NA |
