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. 2015 Jul 10;37(6):1095–1103. doi: 10.1007/s11096-015-0159-3

Table 4.

Negative predictive values within the test Negative group (patients who continued Angiotensin converting enzyme inhibitor)

End of studya Out of studyb Deathc Total minus death Total continuation
NPV at least possible % (95 % CI)
 3 M 95.5 (92.3–97.4) 95.5 (90.6–97.9) 95.0 (88.9–97.8) 95.5 (93.0–97.1) 95.4 (93.2–96.9)
 6 M 94.6 (91.4–96.6) 95.8 (91.6–97.9) 95.8 (90.5–98.1) 95.0 (92.7–96.6) 95.2 (93.1–96.6)
NPV at least probable % (95 % CI)
 3 M 77.9 (72.5–82.4) 75.5 (67.6–82.0) 78.2 (69.2–85.1) 77.1 (72.7–80.9) 77.3 (73.4–80.7)
 6 M 75.9 (70.7–80.4) 74.8 (67.7–80.8) 78.1 (69.9–84.9) 75.5 (71.4–79.2) 76.0 (72.4–79.3)

CI confidence interval, NPV negative predictive value

a“End of study” group are patients who continued ACEIs till January 1st 2011

b“Out of study” group are patients who continued ACEIs till they went out of the area

c“Death” group are patients who continued ACEIs till date of death 3 M and 6 M denote time intervals in months between a renewal of an ACEI prescription and the theoretical end date of the previous prescription