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. 2015 Oct 24;22:97. doi: 10.1186/s12929-015-0201-8

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© Porto et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Pluripotency markers are downregulated by augmented ROS production during aging. The top panels show the correlation between intracellular ROS and ONS transcription factors. Bar graphs show the percentage of positive ONS cells. Values are the means ± SEM, *p < 0.05 vs. young. Abbreviation: Oct-3,4/Nanog/Sox-2 transcription factors (ONS)