Table 2.

The effect of aging on hematological parameters and systemic cytokines profile

Parameters	Groups
	Young	Middle	Aged
Cell Blood Count (CBC)
Red blood cell number (106/ mm3)	4.4 ± 1	7.3 ± 0.2#	7.0 ± 0.3#
White blood cell number (103/ mm3)	2.9 ± 0.4	2.8 ± 0.3	5.3 ± 1
Myeloid (%)	24 ± 4.3	27 ± 4.1	40 ± 4.2*
Lymphoid (%)	76 ± 4.3	73 ± 4.1	60 ± 4.2*
Myeloid Cytokines (pg/mL)
IL-6	256 ± 30	348 ± 34	543 ± 37*
TNF	265 ± 19	398 ± 17	588 ± 80*
IL-12	153 ± 12	187 ± 8	172 ± 16
Lymphoid Cytokines (pg/mL)
IFN-γ	69 ± 1.5	77 ± 2.3	75 ± 3.3
IL-10	516 ± 34	586 ± 22	573 ± 19

Values are means ± SEM for six to 11 animals per group. *p < 0.05 vs young and middle age; #p < 0.05 vs young (one-way ANOVA)