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. 2015 Oct 22;11(10):e1004563. doi: 10.1371/journal.pcbi.1004563

Fig 4. Information transduced by signaling features to downstream transcription factors.

Fig 4

(A) Mutual information between each signaling feature at the snapshot measures of early (20 min as white), intermediate (40 min as gray) and late (58 min as black) phases to downstream transcription factor responses for ppc-FOS:ppc-JUN. (B) Mutual Information between signaling feature and ppc-JUN:ppc-JUN at different snapshot measures. (C) Mutual information between signaling features and Total AP-1. Only FRK and JNK signaling features transferred information to ppc-FOS:ppc-JUN and ppc-JUN:ppc-JUN, respectively, whereas features of both FRK and JNK signals transferred information to Total AP-1.