Table 1. Median binding values of each isolate to mucin from controls and the UC colon and Kruskal-Wallis tests comparing the binding of clinical isolates to that of the reference strain for A. muciniphila and Desulfovibrio spp.
A. muciniphila | Median binding to Control mucin(FU) | IQR | Kruskal-Wallis and Wilcoxin-Mann-Whitney | Fold change in binding compared to the reference strain | Median binding to UC mucin (FU) | IQR | Kruskal-Wallis and Wilcoxin-Mann-Whitney | Fold change in binding compared to the reference strain |
---|---|---|---|---|---|---|---|---|
.077 | .148 | |||||||
Reference | 559.83 | 970.89 | n/a | 2022.41 | 2076.05 | n/a | ||
Healthy isolate | 362.58 | 493.62 | n/a | -0.65 | 1221.52 | 2176.76 | n/a | -0.60 |
UC isolate A | 636.67 | 593.58 | n/a | +1.14 | 3075.48 | 2398.98 | n/a | +1.52 |
UC isolate B | 792.37 | 908.92 | n/a | +1.42 | 3251.41 | 2165.19 | n/a | +1.61 |
Desulfovibrio spp. | ||||||||
<0.005 | <0.005 | |||||||
Reference | 95.10 | 107.73 | n/a | 368.34 | 501.99 | n/a | ||
Healthy isolate | 70.44 | 79.30 | 1.00 | -0.74 | 39.60 | 155.02 | <0.005 | -0.11 |
UC isolate A | 73.94 | 113.35 | 1.00 | -0.78 | 119.74 | 238.59 | .014 | -0.32 |
UC isolate B | 145.38 | 283.64 | .022 | +1.53 | 712.41 | 930.06 | .276 | +1.93 |
Significant values are highlighted in bold text. FU corresponds to measure of bacterial binding in fluorescent units. IQR corresponds to inter quartile range.