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. 2015 Oct 23;10(10):e0141270. doi: 10.1371/journal.pone.0141270

Fig 3. Effect of statins on LOX-1 shedding.

Fig 3

(A) Upper panel shows short and long term treatments of LOX-1-V5 COS transfected cells with atorvastatin (2.5 and 5μM) and lovastatin (1.25 and 2.5μM). Densitometric analysis of fold change of protein band of sLOX-1 over respective time matched controls (lower panel). Data represent the averages ± SEM of three experiments. P < 0.05 (*). (B) Statins treatments of HEK-293 #19 and CHO-F2 cells incubated in serum free medium in the presence of atorvastatin (2.5 and 5μM) and lovastatin (1.25μM) for 24h at 37°C.