Table 4. Stratification analysis for associations between genotypes of Nalp3 and the risk of silicosis.
| IVS8 -7652A>C OR(95%CI) * | Ex4-849C>T OR(95%CI) * | ||||
|---|---|---|---|---|---|
| AA | AC | CC | CC | CT | |
| CDE(mg/m3-y) | |||||
| <120 | 1.00 | 1.16(0.62–2.16) | 1.12(0.47–2.66) | 1.00 | 2.06(0.78–5.45) |
| ≥120 | 1.00 | 0.60(0.31–1.19) | 0.45(0.19–1.05) | 1.00 | 3.05(0.88–10.66) |
| Age(years) | |||||
| <70 | 1.00 | 1.28(0.48–3.42) | 0.24(0.06–0.88) | 1.00 | 1.69(0.36–7.85) |
| ≥70 | 1.00 | 0.77(0.46–1.29) | 1.09(0.54 to 2.18) | 1.00 | 2.52(1.04–6.12) |
| Smoking | |||||
| No | 1.00 | 1.05(0.43–2.55) | 1.59(0.49–5.15) | 1.00 | 1.63(0.25–10.49) |
| Yes | 1.00 | 0.82(0.49–1.39) | 0.61(0.31–1.22) | 1.00 | 2.57(1.11–5.93) |
*ORs were obtained from a logistic regression model that was adjusted for age, smoking status, and CDE.