Table 5. Stratification analysis for associations between genotypes of IL-1β and the risk of silicosis.
-580C>T OR (95%CI) * | Ex5+14C>T OR (95%CI) * | ||||
---|---|---|---|---|---|
CC | CT | TT | CC | CT | |
CDE(mg/m3-y) | |||||
<120 | 1.00 | 0.93(0.47–1.84) | 0.56(0.24–1.27) | 1.00 | 0.14(0.02–1.14) |
≥120 | 1.00 | 0.96(0.48–1.92) | 0.56(0.24–1.31) | 1.00 | 0.96(0.27–3.40) |
Age(years) | |||||
<70 | 1.00 | 0.60(0.22–1.63) | 0.58(0.17–2.02) | 1.00 | — |
≥70 | 1.00 | 1.00(0.58–1.73) | 0.76(0.39–1.49) | 1.00 | 0.54(0.20–1.48) |
Smoking | |||||
No | 1.00 | 1.32(0.52–3.38) | 1.22(0.40–3.74) | 1.00 | 0.25(0.03–2.24) |
Yes | 1.00 | 0.78(0.45–1.36) | 0.57(0.28–1.13) | 1.00 | 0.66(0.21–2.07) |
*ORs were obtained from a logistic regression model that was adjusted for age, smoking status, and CDE.