Fig 2. Example 1 for better representation of the BOLD-topography with 64 electrodes.

27-year-old patient (patient 6, study 3) with left structural frontal lobe epilepsy. The patient underwent a previous operation with frontal resection, which showed a FCD type 2a. No seizure freedom could be achieved through operation. This is a typical example for the superiority of the 64-channel-EEG. The 32-channel EEG reveals a left temporoparietal IED area (A). The 64-channel EEG shows that left frontotemporal regions are as well included in the IED area (B.) The extensive positive BOLD response on the left hand side exactly reflects the IED distribution from temporoparietal to frontotemporal as shown in the 64-channel EEG. The white arrow indicates the relevant positive BOLD response (C and D). (E) shows different IEDs of one IED set.