Table 2. Clinical information.
Patient | Age | m/f | Age of onset | Epilepsy classification | Seizure types | Inter-ictal EEG | MRI | PET/SPECT | AED | Surgery outcome |
---|---|---|---|---|---|---|---|---|---|---|
1 | 36 | m | 7 y | Structural TLE | CPS | F+T right | MTS right | n.a. | LTG LCM | n.a |
2 | 26 | m | 7 y | Structural TLE | CPS | FT bilateral > FT left | Hypothalamic hamartoma | PET: discrete hypometabolism P, T right | LEV OXC LCM | Seedtherapy:not seizure free |
3 | 17 | f | 16 y | Structural TLE | CPS | T + TP right; T left | Unclear mass in the left superior T gyrus | n.a. | OXC | n.a. |
4 | 17 | m | 13 y | Unclear | SPS/CPS GTCS | PO bilateral | Normal | PET: discrete hypometabolism P left | LTG OXC | n.a. |
5 | 27 | f | 16 y | FLE of unclear origin | CPS/GTCS | F bilateral | Normal | PET: normal | LTG LEV | n.a. |
6 | 27 | m | 11 y | Structural FLE | SPS/CPS GTCS | FC, FT left | Surgical cavity left F | PET: extensive hypometabolism TP left | LEV OXC | surgery: not seizure free |
7 | 12 | m | 9 y | Structural FLE | CPS | F bilateral; T left | Cavernoma F right | n.a. | none | n.a. (surgery) out? |
8 | 9 | m | 4 y | Structural FLE | SPS/CPS GTCS | FC bilateral T bilateral | Extensive right polymicrogyria | PET: hypometabolism F, P left | LEV VPA | n.a. |
9 | 28 | f | 11 y | FLE of unclear origin | SPS/CPS GTCS | FP-FC right TP right | Unclear lesion right, F including insular cortex | PET/SPECT: hypometabolism F right | LTG LCM | surgery: not seizure free |
10 | 71 | m | 70 y | Structural TLE | CPS | T pole right | Cystic tumor mesio temporal left | n.a. | VPA | n.a. surgery? |
11 | 31 | f | 31 y | TLE of unclear origin | CPS | T right | n.a. | n.a. | OXC | n.a. |
12 | 60 | m | 40 y | unclear | CPS | T bilateral F bilateral | Defect/gliosis T pole left | PET: hypo metabolism T left | OXC | n.a. |
13 | 13 | m | 3 y | Structural TLE | CPS/GTCS | CP bilateral T bilateral | MTS left and gliosis TP | n.a. | VPA LEV | n.a. |
14 | 23 | m | n.a. | unclear | SPS/CPS GTCS | T right > T left F left O right | abnormal gyration O right | n.a. | LTG CLO | n.a. |
15 | 39 | f | 23 y | TLE of unclear origin | CPS | T bilateral | Hippocampus malrotation left | PET: normal | LTG | n.a. |
16 | 13 | f | 7 y | unclear | CPS/GTCS | FC bilateral; F left | FCD medial-basal right | PET: normal | CAB VPA | n.a. |
17 | 15 | m | 12 y | unclear | SPS/CPS GTCS | FC bilateral P left | n.a. | PET: hypometabolism F left | LTG | n.a. |
AED, anti epileptic drug; C, central; CAB, carbamazepine; CLO, clobazam; CPS, complex partial seizure; f, female; F, frontal; FC, frontocentral; FLE, frontal lobe epilepsy; FP, frontopolar; FT, frontotemporal;GTCS, generalized tonic clonic seizure; LCM, lacosamide; LEV, levetiracetam; LTG, lamotrigine; m, male; MTS, mesial temporal sclerosis; n.a., not available; O, occipital; OXC, oxcarbazepine; P, parietal; SPS, simple partial seizure; T, temporal; TLE,temporal lobe epilepsy; TP, temporoparietal; VPA, valproate acid; y, year