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. 2015 Oct 23;9(10):e0004104. doi: 10.1371/journal.pntd.0004104

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Fig 4 — At the acute visit as well as the convalescent visit (20±10 days), at 90±10 days, at 180±15 days, and at 360±30 days after the acute visit, cytokine concentrations of subjects with (open circles) or without (closed circles) persistent arthralgia were compared to healthy donor controls as well as between MAYV-infected groups by a 2-tailed Mann-Whitney test. An asterisk (*) indicates statistical significance (p<0.05) when compared to healthy controls. The horizontal dotted line represents the median cytokine values for the healthy donor controls. Each circle corresponds to the cytokine concentration of an individual subject and the solid horizontal line represents the mean cytokine concentration of the group. Levels of IL-9 were not significantly different when compared to the healthy control group. Immune mediators on the right are potential predictors of MAYV-induced long-term arthralgia.