Table 3.
Effect of different doses of propolis on serum parameters in INH-RIF induced hepatotoxicity.
AST (IU/L) | ALT (IU/L) | ALP (IU/L) | T.bil (mg/dL) | TP (gm/dL) | CHL (gm/dL) | TG (gm/dL) | |
---|---|---|---|---|---|---|---|
Group I | 145.9 ± 3.391 | 166.5 ± 2.939 | 339.9 ± 3.304 | 0.845 ± 0.385 | 8.260 ± 0.449 | 70.75 ± 3.154 | 57.98 ± 2.297 |
Group II | 303.4 ± 3.654¥ | 359.7 ± 3.269¥ | 515.3 ± 2.191¥ | 2.017 ± 0.497¥ | 4.713 ± 0.169¥ | 271.4 ± 4.335¥ | 165.3 ± 3.036¥ |
Group III | 176.9 ± 3.588# | 205.6 ± 2.802# | 379.6 ± 3.747# | 1.103 ± 0.049# | 6.468 ± 0.177# | 107.1 ± 3.037# | 93.31 ± 2.400# |
Group IV | 234.2 ± 3.346# | 271.7 ± 3.036# | 445.4 ± 3.739# | 1.690 ± 0.025# | 6.125 ± 0.212$ | 195.0 ± 3.519# | 151.8 ± 3.434∗ |
Group V | 290.1 ± 2.959∗ | 341.2 ± 2.737$ | 498.0 ± 3.523$ | 1.830 ± 0.043∗ | 4.263 ± 0.870ns | 256.0 ± 3.587∗ | 158.4 ± 2.860ns |
Values are mean ± S.E.M; n = 6; ¥ P < 0.001, toxic versus normal, ∗ P < 0.05, extract treated groups versus toxic, $ P < 0.01, extract treated groups versus toxic, and # P < 0.001, extract treated groups versus toxic; ns, not significant.