Table 3. Studies reporting on various measures of lymphedema-related morbidity.

Outcome measure	No. of studies	References
Change in ADLA incidence	13	[13, 16–18, 26, 27, 29, 30, 32, 34, 35, 40, 42]
Change in patients reporting at least one ADLA attack/time period	8	[13, 28, 29, 31, 33, 34, 36, 37]
Change in reported quality of life measure *	5	[14, 33, 38–40]
Change in stage or grade of affected limb	4	[32, 37, 39, 41]
Change in leg volume	3	[26, 33, 34]
Change in limb circumference	2	[34]
Change in duration of acute attack	2	[28, 37]
Change in histology of skin punch biopsy	1	[41]
Change in days lost of work	1	[13]

*Defined and measured in various ways across studies, including perceived quality of life, disability, and depression.