Table 3. Hydrogen bonding between thrombin and the bound peptide.

In addition to P1-S1 interactions, also P6-S6 interactions rely on hydrogen bonding. The relatively specific S2 pocket does not show any hydrogen bonding at all.

	S6	S5	S4	S3	S2	S1
Occupancy	1.04	<0.01	0	0.59	0	3.37