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Effect of WY-14643 administration in hepatic injury in steatotic livers subjected to ischemia-reperfusion.
| ALT | ||
|---|---|---|
| Sham | IR | WY-14643 + IR |
| 97 ± 27,85 | 2675 ± 277,03∗ | 380 ± 86,02∗,# |
Alanine aminotransferase (ALT) levels in plasma after 24 h of reperfusion. Sham: anesthesia and laparotomy, IR: 60 min partial ischemia and 24 h of reperfusion, and WY-14643 + IR: iv administration of WY-14643 (10 mg/kg) 1 hour before IR. ∗ P < 0.05 versus Sham; # P < 0.05 versus IR.
