Table 1.
Characteristics of included trials.
| Author Year |
Electronic databases | Assessment tool of primary studies | Study type | Study time | Number of trails (participants) |
Experiment group (participants) |
Control group (participants) |
Course (d) |
Main outcome | Adverse events | Authors' conclusion |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wangand Hu, 2010 [19]※ | VIP, CNKI, and Wanfang | Jadad | RCT | 2000–2009 | 13 (1183) |
CMT plus DHI (623) |
CMT (560) |
7–15 | Effectiveness for RAS and ECG | Yes | Effectiveness of RAS and ECG Incidence of heart event |
|
| |||||||||||
| Xu et al., 2010 [20] |
Cochrane Library, Medline, Embase, CBM disc, and CNKI | Jadad | RCT | 1991–2010 | 9 (771) |
CMT plus DHI (401) |
CMT (370) |
10–15 | Effectiveness for RAS and ECG | No | Effectiveness and safety for UA |
|
| |||||||||||
| Xu et al., 2011 [21] |
Cochrane Library, Medline, Embase, CBM disc, and CNKI | Jadad | RCT | 1991–2009 | 19 (1940) |
CMT plus DHI (991) |
CMT (949) |
10–21 | Effectiveness for RAS and ECG | Yes | Effectiveness for UA |
|
| |||||||||||
| Yang et al., 2011 [22] |
CNKI, Wanfang, VIP, and CBM disc | NM | RCT | 2000–2010 | 12 (1337) |
CMT plus DHI (NM) |
CMT (NM) |
NM | Effectiveness for ECG and RAS | NM | Effectiveness and safety for UA |
|
| |||||||||||
| Cui et al., 2012 [23] |
Pubmed, Medline, CNKI, Wanfang, and Cochrane Library | Jadad | RCT | Up to 2010 | 23 (2675) |
CMT plus DHI (1382) |
CMT (1293) |
10–28 | Effectiveness for ECG and RAS Regulation of HDL-C, LDL-C, and HS-CRP |
NM Or no | Effectiveness for ECG Regulation of HDL-C, LDL-C, and HS-CRP |
DHI: Danhong injection; NM: not mentioned; CMT: conventional medicine treatment, including the combination of platelet aggregation inhibitor (aspirin), nitrates, beta-blockers, calcium channel blockers, and ACE inhibitors; RAS: resolution of angina symptoms; ECG: electrocardiogram; HDL-C: high density lipoprotein-cholesterol; LDL-C: low density lipoprotein-cholesterol; HS-CRP: high sensitive C-reactive protein; ※ indicates the intervention of 2 trials that were conventional medicine treatment plus DHI versus conventional medicine treatment plus Danshen injection; CNKI: China National Knowledge Infrastructure; CBM disc: Chinese Biology Medicine disc.