All MPNs |
IL-6, IL-8, IL-2, soluble IL-2R, HGF, TNF-α, TGF-β, GM-CSF, VEGF, and bFGF |
Bone marrow fibroblasts, endothelial cells, monocytes, macrophages, T-lymphocytes, hematopoietic progenitors, and hepatocytes |
|
ET |
IL-4, IL-10, IFN-γ, MCP-1, PDGF-BB, and soluble IL-6R (gp80) |
M2 macrophages, platelets, and T-lymphocytes |
|
PV |
IL-11, IL-12, IL-13, IL-5, and IL-7 |
Bone marrow fibroblasts, T-lymphocytes, M1 macrophages, and hematopoietic progenitors |
|
PMF |
IL-1β, IL-10, IL-12, IL-13, IL-15, IL-33, G-CSF, IFN-α, MIP-1α, MIP-1β, IP-10, MIG, MCP-1, and PDGF-BB |
Bone marrow fibroblasts, activated T-lymphocytes, neutrophils, macrophages, hematopoietic progenitors, megakaryocytes, and platelets |