Table 1.
Control subjects (20) |
CKD and PD pts (52) |
P | CKD pts with eGFR < 60 > 15 mL/min/1.73 m2 (30) | PD pts (22) |
P | |
---|---|---|---|---|---|---|
Age (years) | 57.8 ± 14.2 | 59.8 ± 161 | >0.05 | 63.6 ± 15.1 | 54.7 ± 16.2 | >0.05 |
Smokers (yes) | 35% | 46% | >0.05 | 52% | 38% | >0.05 |
SBP (mmHg) | 124 ± 8.68 | 140.5 ± 19.65 | <0.01 | 135.3 ± 20.44 | 147.6 ± 16.4 | <0.05 |
DBP (mmHg) | 79.8 ± 5.5 | 90.5 ± 11.22 | <0.05 | 83.7 ± 10.67 | 90.7 ± 11.21 | <0.05 |
Hemoglobin (g/L) | 146.3 ± 11.82 | 117.3 ± 22.48 | <0.01 | 126.4 ± 23.92 | 104.7 ± 12.2 | <0.01 |
Albumins (g/L) | 37.6 ± 1.76 | 34.4 ± 6.02 | >0.05 | 36.8 ± 5.83 | 31.1 ± 4.59 | <0.01 |
CRP (mg/L) | 2.8 ± 1.96 | 9.2 ± 8.81 | <0.01 | 9.8 ± 9.15 | 8.4 ± 8.48 | >0.05 |
Cholesterol (mmol/L) | 5.2 ± 1.37 | 5.7 ± 0.81 | >0.05 | 4.9 ± 1.35 | 5.8 ± 1.26 | >0.05 |
Triglycerides (mmol/L) | 1.9 ± 0.15 | 2.0 ± 1.19 | >0.05 | 1.8 ± 0.79 | 2.4 ± 1.52 | >0.05 |
Uric acid (µmol/L) | 272.9 ± 53.1 | 362.7 ± 104.2 | <0.01 | 364.7 ± 120.8 | 360 ± 79.9 | <0.01 |
BMI (kg/m2) | 22.3 ± 2.2 | 26.6 ± 2.95 | >0.05 | 26.9 ± 3.7 | 25.7 ± 2.2 | >0.05 |
MDA (ng/mL) | 24.9 (12.3–26.9) |
37 (24.1–47.7) |
<0.01 | 37 (27–47.1) |
35.9 (23.7–47.7) |
>0.05 |
MMP-9 (ng/mL) | 321.9 (24–370.9) |
419.4 (350.9–447) |
<0.01 | 420 (390.1–442) |
390 (350.9–464) |
>0.05 |
Results are expressed as mean ± standard deviation or median and interquartile range (25%–75%); pts: patients; CKD: chronic kidney disease; PD: peritoneal dialysis; SBP: systolic blood pressure; DBP: diastolic blood pressure; CRP: C-reactive protein; BMI: body mass index.