Table 1.

Characteristics of the PDAC patients included in the study

Patient Code	Disease Stage	QT before CTC/KRAS cfDNA determination	KRAS cfDNA data	CTC data	CTC/KRAS cfDNA data	DNA concentration in plamsa (Average copies RNaseP/20ul plasma)	KRAS status in plasma	KRAS Mutation in plasma	Ratio M:WT KRAS in plasma	CTC STATUS	Number of CTC	CD45 Depletion KRAS mutation	Mutation in Tissue
1	R	YES	YES			80	NEG						G12D
2	R	YES	YES			43	NEG						G12R
3	R	YES	YES			59	NEG
4	R	NO	YES	YES	YES	106	NEG			NEG	0
5	R	NO	YES	YES	YES	97	NEG			NEG	0	WT	WT
6	R	NO	YES	YES	YES	185	POS	G12D	0,21	POS	1		G12D
7	R	NO		YES						NEG	0	WT
8	R	NO		YES						NEG	0
9	R	NO	YES			86	POS	G12D	0,1			WT	WT
10	R	NO	YES	YES	YES	93	POS	G12D	0,01	NEG	0		G12D
11	R	NO	YES	YES	YES	48	NEG			NEG	0		G12S
12	R	NO	YES	YES	YES	1541	NEG			NEG	0
13	R	NO		YES						NEG	0
14	R	NO		YES						NEG	0
15	LA	NO	YES			52	POS	G12V	0,12
16	LA	NO	YES	YES	yes	6,4	NEG			NEG	0
17	LA	NO	YES	YES	YES	66	NEG			NEG	0	G12D
18	LA	NO	YES	YES	YES	1063	NEG			NEG	0
19	LA	NO		YES						NEG	0
20	LA	YES	YES			297	NEG
21	LA	NO	YES	YES	YES	700	NEG			NEG	0
22	LA	YES	YES	YES	YES	38	NEG			NEG	0
23	LA	NO	YES	YES	YES	111	NEG			NEG	0
24	LA	NO		YES						NEG	0
25	LA	NO		YES						NEG	0	G12D
26	LA	NO		YES						NEG	0
27	LA	NO		YES						NEG	0
28	M	NO	YES			806	POS	G12D	0,06
29	M	NO	YES	YES	YES	12,2	NEG			NEG	0
30	M	YES	YES	YES	YES	1663	POS	G12D	2,43	POS	5		WT
31	M	NO	YES	YES	YES	72	NEG			NEG	0		WT
32	M	NO	YES	YES	YES	1095	POS	G12R	0,02	POS	4		G12R
33	M	NO		YES						NEG	0
34	M	NO		YES						NEG	0
35	M	NO		YES						POS	3
36	M	NO	YES			130	NEG
37	M	NO	YES			147	NEG					G12D
38	M	YES	YES			87	NEG						G12D
39	M	NO	YES	YES	YES	33	NEG			NEG	0		WT
40	M	NO	YES	YES	YES	328	NEG			NEG	0	G12D
41	M	NO	YES	YES	YES	602	POS	G12D	0,81	POS	3
42	M	NO	YES	YES	YES	70	NEG			NEG	0	WT
43	M	NO	YES	YES	YES	52	NEG			POS	1	WT
44	M	NO		YES						NEG	0
45	M	NO		YES						POS	13

R Resectable, LA Locally Advanced, M Metastatic