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. 2015 Oct 24;15:792. doi: 10.1186/s12885-015-1782-z

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© Ducasse et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Variation in time to switch between division and differentiation results in significant cell number differences inspite of the same starting stem cell numbers. a Stop of proliferation and start of differentiation after three generations lead to a larger differentiated tissue mass. b Stop of proliferation after one generation and start of differentiation earlier than A, result in a smaller differentiated tissue mass