Table 2.
Dynamics of MHC-I and MHC-II molecules in spleen lymphocytes
| Marker (%) | Time point | Groups (n = 5) | |||
|---|---|---|---|---|---|
| Blank | PBS | PVAXI | PVAX-EF-1a | ||
| MHC-I | Week 0 | 18.19 ± 2.46 | 17.17 ± 2.62 | 16.99 ± 1.38 | 17.29 ± 2.34 |
| Week 2 | 16.55 ± 2.15 | 17.13 ± 1.91 | 17.06 ± 2.44 | 24.23 ± 3.33a | |
| Week 4 | 17.64 ± 1.82 | 18.02 ± 1.91 | 17.62 ± 1.46 | 31.44 ± 3.54a | |
| Week 6 | 17.88 ± 1.78 | 17.76 ± 1.16 | 18.14 ± 2.30 | 32.96 ± 3.04a | |
| MHC-II | Week 0 | 3.07 ± 0.97 | 2.88 ± 0.37 | 3.31 ± 0.49 | 3.27 ± 0.61 |
| Week 2 | 2.99 ± 0.71 | 3.17 ± 0.38 | 3.07 ± 0.97 | 4.84 ± 1.86a | |
| Week 4 | 3.25 ± 0.45 | 3.17 ± 0.38 | 3.27 ± 0.59 | 7.52 ± 1.42a | |
| Week 6 | 3.22 ± 0.56 | 3.11 ± 0.73 | 3.24 ± 0.53 | 8.26 ± 1.23a | |
Data are presented as the mean ± SD (n = 5). a represents statistically highly significant difference (p < 0.01) as compared with control groups: Blank, PBS and pVAXI