Table 2.
The genotype distribution of rs864745 (JAZF1) and rs796158 (TSPAN8/LGR5) polymorphisms in T2DM and control group
| Control n (%) | T2DM n (%) | Odds ratioa (95 % CI) | p value | Odds ratiob (95 % CI) | p value | |
|---|---|---|---|---|---|---|
| JAZF1 (rs864745) | ||||||
| AA | 189 (47.25) | 137 (34.25) | Reference | Reference | ||
| AG | 165 (41.25) | 186 (46.5) | 1.5 (1.2, 2.1) | 0.004 | 2.1 (1.3, 3.4) | 0.002 |
| GG | 46 (11.5) | 77 (19.25) | 2.2 (1.4, 3.4) | 0.0001 | 1.9 (1.2, 3.1) | 0.005 |
| AG + GG | 211 (52.75) | 263 (65.75) | 1.7 (1.2, 2.1) | 0.0001 | 2.0 (1.3, 3.2) | 0.001 |
| AA + AG | 354 (89.5) | 323 (80.75) | 0.5 (0.3, 0.8) | 0.002 | 0.8 (0.4, 1.5) | 0.003 |
| TSPAN8 (rs7961581) | ||||||
| CC | 63 (15.8) | 55 (13.8) | 0.90 (0.59, 1.4) | 0.63 | 1.0 (0.66, 1.6) | 0.86 |
| TC | 138 (34.4) | 153 (38.2) | 1.1 (0.84, 1.4) | 0.37 | 1.2 (0.82, 1.6) | 0.41 |
| TT | 199 (49.8) | 192 (48.0) | Reference | Reference | ||
| CC + TC | 201 (50.2) | 208 (52.0) | 1.07 (0.81, 1.4) | 0.72 | 1.1 (0.82, 1.5) | 0.47 |
| TT + TC | 337 (84.2) | 345 (86.2) | 1.1 (0.79, 1.73) | 0.42 | 1.1 (0.81, 1.75) | 0.38 |
aCrude odds ratio (95 % CI)
bOdds ratio (95 % CI) controlled for age, gender and BMI