Table 1.

Patient characteristics and TNIK expression in stage I-III CRC patients

Variables		TNIK expression		p value
		Low (n = 139)	High (n = 81)
Age	< 70 years	98	53	0.435
	≥ 70 years	41	28
Gender	male	88	60	0.102
	female	51	21
Histology (TNM 7th)	G1	62	28	0.258
	G2	70	46
	G3	7	7
Tumor location	right-sided colon	26	28	0.016
	left-sided colon	58	22
	rectum	55	31
Stage (TNM 7th)	I	36	12	0.104
	II	55	32
	III	48	37
Depth of tumor invasion (TNM 7th)	T1	17	6	T1-3 vs. T4 0.002
	T2	32	11
	T3	58	29
	T4	32	35
Lymphatic invasion	(-)	50	17	0.021
	(+)	89	64
Venous invasion	(-)	27	6	0.020
	(+)	112	75
Lymph node metastasis	(-)	91	44	0.102
	(+)	48	37
CEA*1	< 5 ng/ml	101	52	0.189
	≥ 5 ng/ml	38	29
Distant recurrence	(-)	118	49	< 0.001
	(+)	21	32

CEA*¹ carcinoembryonic antigen