Table 2.

Correlation of CD68-positiveTAMs in the tumor invasive front with clinicopathological characteristics of hilar cholangiocarcinoma

Clinicopathological analysis	ᅟ	ᅟ	ᅟ
Variable	high CD68	low CD68	p
No. of patients	26	21
Gender			0.552
Male	13 (50 %)	10 (47.6 %)
Female	13 (50 %)	11 (52.4 %)
Patient age, years			0.448
≤60	14 (53.8 %)	12 (47.6 %)
>60	12 (46.2 %)	11 (52.4 %)
Histological differentiation			0.307
Well/moderate	21 (80.8 %)	19 (90.5 %)
Poor	5 (19.2 %)	2 (9.5 %)
Pathological T stage			0.413
T2	8 (30.8 %)	8 (38.1 %)
T3	18 (67.9 %)	13 (61.9 %)
Pathological N stage			0.307
Negative	19 (73.1 %)	13 (61.9 %)
Positive	7 (26.9 %)	8 (38.1 %)
Perineural sheath infiltration			0.390
Negative	3 (11.5 %)	1 (4.8 %)
Positive	23 (88.5 %)	20 (95.2 %)
Lymphangiosis carcinomatosa			0.576
Negative	12 (46.2 %)	10 (47.6 %)
Positive	14 (53.8 %)	11 (52.4 %)
Perivascular lymphangiosis			0.552
Negative	13 (50 %)	11 (52.4 %)
Positive	13 (50 %)	10 (47.6 %)
Vascular invasion			0.549
Negative	18 (69.2 %)	14 (66.6 %)
Positive	8 (30.8 %)	7 (33.3 %)
Tumor recurrence			0.015
Without	8 (30.8 %)	14 (66.7 %)
With	18 (69.2 %)	7 (33.3 %)
Local recurrence			0.001
Without	9 (34.6 %)	18 (85.7 %)
With	17 (65.4 %)	3 (14.3 %)
Distant metastases			0.390
Without	19 (73.1 %)	17 (81.7 %)
With	7 (26.9 %)	4 (19.0 %)