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. Author manuscript; available in PMC: 2015 Oct 25.
Published in final edited form as: Pharm Dev Technol. 2013 Sep 19;19(7):806–812. doi: 10.3109/10837450.2013.836216

Table 3.

Model comparison: Summary of statistics for Y1, Y2 and Y3 responses.

Models p-value R2 Adjusted R2 Predicted R2 SD PRESSa Remarks
Response (Y1)
  Linear 0.0002 0.7909 0.7529 0.6706 0.35 2.12 Suggested
  Quadratic 0.1059 0.8987 0.8354 0.7415 0.29 1.66
  Special Cubic 0.1389 0.9276 0.8655 0.6333 0.26 2.35
Response (Y2)
  Linear < 0.0001 0.9351 0.9233 0.8983 0.37 2.41 Suggested
  Quadratic 0.4495 0.9525 0.9229 0.8511 0.37 3.53
  Special Cubic 0.2531 0.9611 0.9278 0.8104 0.36 4.49
Response (Y3)
  Linear < 0.0001 0.8847 0.8638 0.8170 4.18 304.83 Suggested
  Quadratic 0.2332 0.9305 0.8870 0.7988 3.80 335.12
  Special Cubic 0.0798 0.9565 0.9193 0.8529 3.22 245.0
a

PRESS is predicted residual sum of square