Table 6. Median value (95% CI) of leukocyte differential count and C-reactive protein vs. Sequential Organ Failure Assessment (SOFA) score in different class of patients with or without liver disease admitted in intensive care unit (ICU).

Parameters	No hepatopathic patients					Hepatopathic patients
	SOFA <5	SOFA 6-10	SOFA 11-15	SOFA >15		SOFA <5	SOFA 6-10	SOFA 11-15	SOFA >15
Leukocytes (×109/L)	10.57γ (10.23-10.99)	9.48ε (8.86-10.50)	10.21ζ (7.69-15.26)	19.48¶ (16.78-21.87)		9.89γ (6.47-13.39)	9.01ε (6.73-11.92)	9.68ζ (6.98-11.41)	12.46 (8.59-18.17)
Neutrophils (×109/L)	8.32γ (7.88-8.89)	7.77ε (7.41-8.39)	8.60ζ (6.74-13.87)	18.67¶ (15.82-21.31)		8.48 (4.42-9.92)	7.87 (5.54-9.63)	8.72 (5.52-10.26)	9.09 (6.40-15.85)
Lymphocytes (×109/L)	0.91α¶ (0.88-0.96)	0.79δε (0.72-0.88)	0.49 (0.37-0.84)	0.32¶ (0.29-0.43)		1.26α (0.85-1.93)	0.58 (0.42-1.09)	0.52 (0.45-0.63)	0.61 (0.54-0.77)
Monocytes (×109/L)	0.80α (0.75-0.84)	0.64δε (0.58-0.72)	0.34¶ (0.26-0.54)	0.25¶ (0.22-0.35)		0.89α (0.73-1.19)	0.65ε (0.42-0.95)	0.64ζ (0.53-0.76)	1.13 (0.78-1.56)
Immature granulocytes (×109/L)	0.17α (0.15-0.19)	0.13ε¶ (0.10-0.18)	0.13ζ¶ (0.07-0.18)	2.38¶ (1.71-2.84)		0.15α (0.06-0.37)	0.35 (0.12-0.55)	0.30 (0.21-0.49)	0.35 (0.27-0.56)
Highly fluorescent cells (×109/L)	0.01γ (0.01-0.02)	0.01ε¶ (0.01-0.02)	0.01ζ (0.00-0.02)	0.05 (0.03-0.10)		0.01 (0.00-0.03)	0.00 (0.00-0.01)	0.02 (0.01-0.03)	0.03 (0.01-0.08)
C-reactive protein (mg/dL)	8.2α (7.0-9.6)	7.4δε¶ (6.0-10.5)	17.6¶ (14.9-24.8)	17.4¶ (16.0-20.8)		7.6 (4.5-13.0)	5.6 (3.7-9.0)	3.8 (2.3-5.2)	4.7 (4.2-5.7)

Statistically significant differences by Steel-Dwass-Critchlow-Fligner and by Kruskal-Wallis test with P<0.001: ^γ, SOFA <5 vs. >15; ^ε, SOFA 6-10 vs. >15; ^ζ, SOFA 11-15 vs. >15; ^¶, no hepatopathic patients vs. hepatopathic patients in the same class of SOFA score; ^α, SOFA <5 vs. 6-10, 11-15 and >15; ^δ, SOFA 6-10 vs. 11-15.