Table 3.
Data derived from studies that have evaluated apparent diffusion coefficient quantification of pancreatic ductal adenocarcinomas with different degree of differentiation
| Ref. | No. of patients | Field strength (T) | b-values (s/mm2) | Mean ± SD ADC (× 10-3 mm2/s) | P value |
| Wang et al[20] | 21 | 1.5 | 0, 500 | 2.10 ± 0.42 (MD-WD) | < 0.05 |
| 1.46 ± 0.17 (PD) | |||||
| Legrand et al[21] | 22 | 1.5 or 3 | Multiple1 | 1.43 ± 0.12 (WD) | 0.05 |
| 1.94 ± 0.62 (MD-PD) | |||||
| Muraoka et al[44] | 10 | 1.5 | 0, 500 | 1.88 ± 0.39 (loose fibrosis) | < 0.05 |
| 1.01 ± 0.29 (dense fibrosis) | |||||
| Rosenkrantz et al[45] | 30 | 1.5 | 0, 500 | 1.78 ± 0.33/1.75 ± 0.49 (MD-WD)2 | NS |
| 1.69 ± 0.36/1.62 ± 0.33 (PD)2 | |||||
| Fukukura et al[46] | 92 | 3 | 0, 1000 | 1.10 ± 0.09 (high cellularity) | < 0.05 |
| 1.25 ± 0.18 (low cellularity) |
1
0, 50, 200, 400, 600, 800 s/mm2;
2
Two readers. T: Tesla; WD: Well differentiated PDAC; MD: Moderately differentiated PDAC; PD: Poorly differentiated PDAC; ADC: Apparent diffusion coefficient; PDAC: Pancreatic ductal adenocarcinoma; NS: Not statistically significant.