TLR expression on monocytes. TLR-2, -4, -5, and -6 are membrane bound, whereas TRL-3, -7, and -9 are intracellular and were analyzed following fixation with respective antibodies and isotype controls. Numbers in the parenthesis are mean fluorescence channel numbers (MFC#) as an indicator of density of molecules. TLR-4 expression is increased, whereas the expression of TLR-5, -7, and -9 is decreased.