Table 1.
Multivariate Cox Proportional Hazards Model in Estrogen Receptor-Positive Breast Cancers
| Variables | Beta | p-Value | Risk ratio | Risk ratio 95% lower | Risk ratio 95% upper |
|---|---|---|---|---|---|
| XRCC1 | −0.203954 | 0.000219 | 0.815500 | 0.731907 | 0.908640 |
| FEN1 | 0.199727 | 0.004731 | 1.221069 | 1.063067 | 1.402556 |
| SMUG1 | −0.210251 | 0.003919 | 0.810381 | 0.702510 | 0.934816 |
| APE1 | −0.245472 | 0.000754 | 0.782335 | 0.678241 | 0.902406 |
| Lymph node stage (continuous) | 0.705445 | 0.0000001 | 2.024747 | 1.662938 | 2.465276 |
| Histological grade | 0.616616 | 0.0000001 | 1.852647 | 1.510526 | 2.272256 |
Bold values indicate significant p-values.
APE1, AP endonuclease 1; FEN1, flap endonuclease 1; SMUG1, single-strand monofunctional uracil glycosylase-1; XRCC1, X-ray cross-complementation group 1 protein.