Figure 1.

Somatic and dendritic distribution of Golgi apparatus in spinal motor neurons. Projection of confocal sections (optical thickness = 15 μm) of a retrogradely Cholera toxin B (CTB) labeled motor neuron double labeled for cis-Golgi matrix protein GM130 (van Dis et al., 2014). CTB outlines the somato-dendritic compartment of labeled motor neurons, accumulating in the cytoplasm, trans-Golgi and lysosomes. GM130 immunoreactivity is associated with an extensive perinuclear network of thread-like profiles, that in motor neurons may enter into the initial part of one or more dendrites. This example shows one GM130-positive profile extending in the center of the dendrite up to the first branching point (arrow), while other dendrites (d2, d3) do not show Golgi profiles. In other neurons the Golgi profiles may extend up to the second branching point, or multiple profiles running parallel may invade a single dendrite (Gardiol et al., 1999; van Dis et al., 2014). Asterisks, Golgi apparatus of glia cells; Bar = 10 μm.