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. 2015 Oct 12;5(5):416–430.

Table 1.

PET findings in the area of seizure focus in patients with epilepsy

PET study Findings
Interictal 18F-FDG Usually reduced metabolism
Ictal 18F-FDG Increased and decreased metabolism (complex pattern)*
Post-ictal 18F-FDG metabolism** Complex pattern, increased or decreased
GABAA-cBZR receptor Reduced binding
Opioid receptor Increased mu and delta receptor bindings
Serotonin receptor Reduced binding
Dopamine receptor Reduced binding
11C-alpha-methyl-L-tryptophan Increased uptake
Interictal 15O-H2O Usually reduced perfusion
Ictal 15O-H2O Increased perfusion
*

due to long brain uptake period of FDG;

**

depending on the time of injection after seizure.