Table 2.
Relative representation and light scatter properties of blood CD56+low CCR5/CXCR3−, CD56+int CCR5/CXCR3+, and CD56+high CCR5/CXCR3+ NK-cell subsets.
| A | B | C | P values | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CD56+low
CCR5/CXCR3− |
CD56+int
CCR5/CXCR3+ |
CD56+high
CCR5/CXCR3+ |
A versus B | B versus C | A versus C | ||||
| % CD56+ NK-cells | 90.3 ± 3.9 | (83.4–98.0) | 6.1 ± 4.0 | (1.2–14.6) | 3.7 ± 2.3 | (0.9–8.5) | — | — | — |
| FSC | 299 ± 9 | (285–315) | 303 ± 10 | (284–320) | 311 ± 11 | (291–324) | n.s. | 0.044 | 0.041 |
| tSSC | 151 ± 7 | (140–163) | 156 ± 7 | (141–170) | 159 ± 5 | (147–168) | n.s. | n.s. | n.s. |
Data were obtained using the gating and analysis strategies described in Figure 2, where representative dot plots of these three NK-cell subsets are presented.
Results are expressed as mean ± standard deviation (minimum–maximum) of the percentage of each NK-cell subset within total CD56+ NK-cells and as mean ± standard deviation (minimum–maximum) of the transformed side scatter (tSSC) and forward scatter (FSC) channel of each NK-cell subset.
n.s.: not statistically significant.